The History of Blood Cell Labeling 1976 - 2001

The landmark events in the history of the International Society of Radiolabeled Blood Elements (ISORBE) can be traced back to more than two decades ago at the MRC Cyclotron Unit, Hammersmith Hospital in London, U.K, when Drs. John McAfee who then was at State University of New York, Syracuse, was on sabbatical leave at MRC Cyclotron Unit (July to December 1974) and Mathew Thakur surveyed more than 50 soluble and particulate agents to label human white blood cells (WBCs) with a gamma emitting radionuclide.

Drs. John McAfee and Mathew Thakur more than 20 years ago, when they were working together at the Hammersmith Hospital, London, UK

Bombarding a large number of metal ions or their compounds in a fixed energy 30" diameter cyclotron, Mathew Thakur prepared such gamma emitting radionuclides as Fe-52, Zn-62, Rb-81, Pb-203, I-123, In-111 and Ga-67 and converted them into a variety of suitable chemical forms for WBC labeling. Using a generator produced Tc-99m several other compounds were also prepared. These were then examined for labeling white blood cells separated from plasma. The work went on non-stop for full six months, during which time each of them donated blood every other working day. Consuming fatty meals or even coffee or tea with cream 30 - 45 minutes prior to drawing blood was prohibited for it retarded blood sedimentation.

It was then Mathew Thakur's turn to go on sabbatical (June 1975 - May 1976) to Dr. Michael Welch's group at Mallinckrodt Institute of Radiology (MIR), Washington University, St. Louis. There he choose to work with In-111-oxine which appeared to be a most promising agent. It was in St. Louis where the first abscess images in dogs were obtained. Furthermore, platelets have been labeled as well with In-111-oxine and experimental deep venous thrombosis was detected by scintigraphy. The facility was excellent and the cooperation of Drs. R.E. Coleman, M.J. Welch and their colleagues was outstanding. „ It turned out to be the most exciting and highly successful year of my career. Every erperiment I did at St. Louis was successful. I wish this could happen all the time,"recalls Mathew Thakur.
The hard work resulted in some important publications as for instance Indium-I I I labeled platelets: Studies on preparation and evaluation of in vitro and in vivo function from the authors M.L. Thakur, M.J. Welch, H. Joist and R. E. Coleman published in Thromb. Res.4, 345-357 in 1976, or Indium -111- labeled leukocytes for the localization of abscesses: preparation, analysis, tissue distribution, and comparison with Gallium-67-citrate in dogs from M.L. Thakur, RE. Coleman and M.J. Welch, published in the Journal of Laboratory and Clinical Medicine, 89, 217 - 228 in 1977.

Dr. Thakur then went back to Hammersmith and worked with Professor Ford at the University of Manchester and labeled lymphocytes with In-111-oxine. At Hammersmith, using In-111-oxine labeled WBC, he worked with Dr. J.P. Lavender and by the end of 1976 they studied 20 patients with known abscesses or with fever of unknown origin. Using In-111 labeled lymphocytes they also studied a few patients with Hodgkin's disease. The results have been published in the British Medical Journal (1977, 2, 797-799) by the authors J.P. Lavender, J.M. Goldman, R.N. Arnot and M.L. Thakur under the title
Kinetics of Indium-111 labelled lymphocytes in normal subjects and patients with Hodgkin's disease.

In February 1977, Mathew took a position with Dr. Alexander Gottschalk in the Department of Radiology at Yale University School of Medicine and worked with a cardiologist, Drs. B. Zaret and A. Riba, demonstrating the application of In-111 labeled platelets in detecting experimental bacterial endocarditis and coronary artery thrombosis. Twenty patients with known myocardial infarction were also studied with In-111-WBC and infarcted myocardium was successfully delineated. Imaging experimental infective endocarditis with Indium-lll-labeled blood cellular components (Circulation 59, 336-343, 1979) and Imaging experimental coronary artery thrombosis with Indium-111 platelets (Circulation 60, 767-775, 1979) from the authors A.L. Riba, M.L. Thakur, A. Gottschalk, V.T. Andriole and B.L. Zaret are publications from this period.

By this time, the Diagnostic Isotopes had already begun to produce In-111-oxine for limited supply within the USA. Supported by Diagnostic Isotopes, Drs. Thakur, Gottschalk and Zaret organized the first symposium on radiolabeled cellular blood elements which was held in November 1979 in New York. This generated a tremendous impetus amongst the investigators in a variety of disciplines throughout the world. By early 1980, at one time there were as many as 600 Investigational New Drug (IND) applications filed with the USA Food and Drug Administration (FDA). In 1985 In-111-oxine was approved by the FDA as a low risk substance.
In 1982, NATO provided nearly US$ 40.000,- to hold an advanced study institution in Maratea, Italy, for two weeks. The meeting held in an isolated hotel looking the Mediterranean permitted to researchers corning from all over the world, to discuss deeply both, the basic principles and the clinical applications of radiolabeled blood elements; it could probably be considered the starting point for the widespreading of clinical applications. Since then, once in every two or three years an international symposium on radiolabeled blood elements is held. In addition there have been pre- or post-congress meetings connected with the EANM-Conferences, such as those in Dusseldorf, 1994 and in Copenhagen, 1996. The chronology of these events provided in the
time-table.

When Mathew Thakur visited Helmut Sinzinger in Vienna in 1988 they got together in a rural style restaurant named D'Rauchkuchl to discuss the organization of the forthcoming meeting and they also talked about their experience in labeling blood cells. Among other issues, they discussed was the number of scientists working in the field of labeled blood cells. The number was increasing exponentially, so they decided to found a Society dealing with this topic. During the 5th International Symposium on Radiolabeled Blood Elements in 1989 in Vienna the International Society of Radiolabeled Blood Elements (ISORBE) was established and was registered in Vienna on August 20th, 1990.


Abb. LABEL ISORBE

This sign has been created by Ernst Havlik, a physicist at the Department of Nuclear Medicine in Vienna, to represent ISORBE



In 1992 Mathew Thakur received the Paul Aebersold Award at the SNM Annual Meeting for his outstanding achievements in Nuclear Medicine. Mathew has an outstanding ability to bridge the gap between basic chemistry and its successful application to clinical problems the very thing for which this award is given wrote David A. Goodwin, Chief of Nuclear Medicine, Palo Alto, CA. Among many others receiving recognition by Peers for their contribution to the field were John McAfee, Jose Martin-Comin and Helmut Sinzinger who was awarded twice in 1992 for his work in the field of labeled blood elements. The first was the CIS Jean Debiesse Award which he received during the EANM-Congress in Lissabon for the work on radiolabeling of low-density lipoproteins for the imaging of atherosclerosis. The second one was handed over m Paris m September for the clinical research on Evidence for increased vascular monocyte uptake in patients with heterozygous familial hypercholesterolemia in-vivo during the International Angiology Conference.

One day in June late in the evening the phone rang in Hehmut Sinzinger's office; Mathew Thakur called from the States and asked him whether he would be ready to become the next president. At the 6th International Symposium of the ISORBE in November 1992 in Barcelona, Spain, Helmut Sinzinger was elected to become the second President of the society for the next three years. As the secretary for ISORBE John McAfee had taken the membership administration task in which he did a superb job. The logo of the meeting (the organizers offered a keyholder to all speakers) was the basis for the ISORBE logo, finally designed by Ernst Havlik. The first draft of it was designed together with Mathew Thakur.

During the period of Helmut Sinzinger's Presidency the Society started to provide the members,  for the first time, with Newsletters, which were published only at irregular intervals.

Since its initiation 20 years ago, the work in the field has continued to grow. On Saturday, the 20th of August 1994, during the European Association of Nuclear Medicine Congress m Dusseldorf, Germany, the Society organized, for the first time, a pre-congress meeting, where the latest findings on imaging inflammation and vascular lesions were presented. This was followed by an extremely lively round table discussion. In the evening all the members of the board of directors attending the EANM-conference met for dinner in a delightful fish-restaurant in the center of Dusseldorf and talked on some details about the forthcoming ISORBE-meeting in 1995 at the Yale University, New Haven, USA, to be organized by Mike Ezekowitz, his colleagues and the helping hand of Paulette Trent.

In the course of the meeting at Yale University in New Haven 1995 Jose Martin-Comin was elected unanimously to become the third president of the ISORBE.

Martin-Comin hosted a dinner for the Board of Directors, for it was the time to talk about the 8th International Congress of the ISORBE in Rome more in detail.

The present meeting in Rome is organized by Alberto Signore, who is at the present time the Secretary of ISORBE. He is doing an outstanding job for the Society during the past two years and and made the Newsletters with scientific contributions, paper banks and information on forthcoming events available to the members at a regular interval. The publication of suggested methodologies for blood cell labeling and the regular appearance of ISORBE News in the European Journal of Nuclear Medicine are the closest projects.

The scientific program in Rome in May 1997 is expected to be highly educational professionally beneficial and socially enjoyable. Alberto has managed to invite most prominent investigators in the field of atherosclerosis and thrombosis (Russel Ross, Valentin Fuster) and to attract a large number of abstracts. The ISORBE-family of researchers can look forward to an exciting week in Rome.

Today, more than 20 years later, labeled blood cells/elements examinations are routinely practiced in most Nuclear Medicine Departments. The clinical impact of these examinations on patients management is quite important in different pathologies. Nevertheless, the research for better, more specific, simple and safe agents and techniques continues and the challenge of ISORBE is to contribute to this progress.

AWARDS 

Premio JEN-1986 concedido por la Junta de Energia Nuclear al trabajo: ,,Utilidad de la gammagrafia con leucocitos-111In-oxina en el brote agudo de la enfermedad inflamatoria intestinal. R. Villa, J. Martin-Comin, J.J. Gine, T. Casanovas, A. Ybern y M.A. Gasull. Palma de Mallorca, Junio de 1986

Accesit al mejor trabajo publicado en la Revista de la S.E.M.N.,,Marcaje de Leucocitos con 99mTc-HMPAO. Estudio Metodologico."M.Roca, J. Mora, M.L. Prat, J. Daumal, C. de la Fuente y J. Martin-Comin. Rev. Esp. Med. Nuclear 8: 3-7, 1989.

Paul Aebersold Award for the scientific work in labeling blood cells, monoclonal antibodies and peptides at the SNM Annual Meeting in 1992 for Mathew Thakur.

CIS Jean Debiesse Award for the work on radiolabeling of low-density lipoproteins for the imaging of atherosclerosis during the EANM-Congress in 1992 for Helmut Sinzinger.

Helmut Sinzinger's presentation,evidence for increased vascular monocyte uptake in patients with heterozygous familial hypercholesterolemia in vivo“ was awarded during the International Angiology Conference in September 1992

*This is just a selection, not a complete list  



Awards

Following Mathew Thakur's information this meeting was attended by about 60 investigators from the USA and Canada. It was organized by Drs. Thakur, Gottschalk and Zaret and fully supported by the late Mr. James Finn, president of Diagnostic Isotopes, NJ, the company which made In-111-oxine commercially available first. The company was later bought by Medi-Physics, which paid for the publication of the first book on the subject, edited by Thakur and Gottschalk. The impetus generated by the success of this meeting prompted Mathew Thakur to organize the first International Symposium on the subject in 1982. This meeting is frequently referred as the NATO- or the Maratea-meeting.

This meeting, for a variety of reasons, has provided the most vivid memories to most of its participants. Despite a few unpleasant events, mostly related to the warm tropical climate in Maratea, a tiny village at the west coast of Italy, approximately 100 miles from Naples. This ten days meeting was most enjoyable, socially as well as professionally. Many participants of this meeting became life-long friends, and it may not be an exaggeration to say that it is that friendship and the loyalty to the subject matter of the meeting led to the formation of ISORBE. A large proportion of the funding for the meeting was provided by NATO, although its organizers gratefully acknowledged the support made available by Medi-Physics, Amersham International, Mallinckrodt Inc. and Beckman International. Mathew Thakur, the director, with his equally able co-directors Max Hardeman and Michael Ezekowitz, invited many prominent speakers of international reputation to give plenary lectures and encouraged many newcomers to attend the meeting.





Helmut Sinzinger during his lecture

111 Indium has been established as the radioisotope of choice for the study of platelet and granulocyte kinetics. Mike Ezekowitz was presenting a movie in which his technician Eileen O. Smith was showing their optimized procedure for labeling of platelets. An intensive and sometimes hot discussion was surrounding the optimal labeling methodology for platelets and white blood cells. The scientific program not only included didactic lectures and scientific presentations in a large theater of a hotel on the top of a steep hill, 100 feet above a clean, sunny beach but also of open ground discussions during pizza parties, soccer- and volleyball games, during fishing trips and a trip to historical Pompeii. The wasps and ants were also friendly: they frequently followed the guests into their rooms, their beds, the dining hall and sometimes, even into the sandwiches of most affectionate people like Eva Jager. When the elevator failed, we climbed nearly 150 steps to the hotel from the beach. When David Goodwin accidentially lost his wallet m the sandy base of the 15 foot deep, clear blue ocean, we retrieved it. When John McAfee lost his only pair of glasses during a boat trip, we found them. The Italian wine regularly served at dinner time, showed its presence in the stomachs of a few, but most did not mind it. Food normally was served late and cold, but only a few, as eg Vera Fitscha, managed to lose their appetite for it. The climate was perfect for,funghi porcini", which we were enjoying repeatedly. It was the first time the crowd discovered how avid a soccer player Jose Martin-Comin was, and how charming Wolfgang Becker looked even then without a beard. Mathew Thakur pretended to be busy for most of the time, but managed to play basketball with the sleeves of his shirt rolled down to his wrists. And so on! What a great meeting it was!


List
of participants: W. Adam, Germany; S. Aydar, Turkey; P.N. Badenhorst, RSA; W. Becker, Germany; D.M. Bellotto, Canada; L. Boutal, UK; F. Brady, UK; M. Budabin, USA; R Claessens, The Netherlands; M.E. Clay, USA; L. Crawford, USA; E. Deisenhammer, Austria; E. Dienstl, Austria; J.G. Doorenspleet, The Netherlands; A. Driedger, Canada; F. Eckhard, Germany; M. Ekman, Sweden; D. English, USA; G.J. Easing, The Netherlands; J. Fehr, Switzerland; P. Fitscha, Austria; L.A. Forstrom, USA; G.F. Fueger, Austria; P. Gerundini, Italy; F. Gokan, Turkey; G. Grimfors, Sweden; A. Grossi, Italy; A.A. Guerrero, Spain; U. Guven, Turkey; R Haznedar, Turkey; J. Hiltunen, Finland; S. Hoory, USA; M. Horvath, Hungary; S.E. lace, UK; E. Jager, Austria; Ch. Kessler, Germany; J.B. Laidler, UK; P. Lavender, UK; J. Le Cloirec, France; A. Levasseur, Canada; F. Lomena, Spain; F. Loumas, Australia; C. Lundburg, Sweden; J. Martin-Comin, Spain; B.H. Mock, USA; A. Moisan, France; D.D. Munjal, USA; S.N. Nielsen, Denmark; D. Orkide, Turkey; C.P. Page, UK M.A. Peters. UK; D. Picard, Canada; C. Piera, Spain; C. Pozzilli, Italy; M. Quastel, Israel; J.W. Rasmussen, Denmark; C. Raymonde, Canada; M. Roca, Spain; J.-E. Ryser, Switzerland; A. Signore, Italy; H. Sinzinger, Austria; E.O. Smith, USA; S. Tassmari, USA; M. Thakur, USA; H.M. Towler, UK; K Uno, Japan; P.J. Voogt, The Netherlands; H.W. Wagner, USA; A. Warbick-Cerone, Canada; Y.G. Zorbas, Greece



3rd Meeting Bloemfontein 1986:



Anthon du P. Heyns, his wife and Wolfang becker enjoying dinner




 




 


In a memorable journey we were taken by our hosts tour to the Krueger National Park. Starting close to midnight (i.e. 4:00 a.m) we were driven with jeeps from Bloemfontein to the park. Immediately at the entrance we were greeted by a family of lions, later on seeing an impressive picture of buffalo herd, elephants, giraffes, antilopes, hyenas. and many others. A group of monkeys we were disturbing during their lunch time sitting on and around trees. The overnighting in the camps including the outdoor grilling were unique events as well. After this unforgettable trip some of us were presentmg lectures at different places in South Africa, among them in Durban and Capetown. We got an impression on the political situation of South A&ica for it was the period of time where they started seriously to stop the ethnical separation.

 





Our Southafrican colleagues during the trip through Krueger National Park

 

List of participants:

P.N. Badenhorst, Bloemfontein, RSA; G.M.B. Berger, Rondebosch, RSA; N. Chetty, Johannesburg, RSA; P.J. Commerford, Observatory, RSA; E.B. Dowdle, Observatory, RSA; A. Eldor, Jerusalem, Israel; M.D. Ezekowitz, New Haven, USA; R.C. Franz, Pretoria, RSA; W. Gevers, Observatory, RSA; R.S. Hanson, La Jolla, USA; M.R. Hardeman, Amsterdam, NL; L.A. Harker, La Jolla, USA; A. du P. Heyns, Bloemfontein, RSA; E.J. Immelman, Observatory, RSA; H.F. Kotze, Bloemfontein, RSA; R. Lijnen, Leuven, Belgium; M.G. Lotter, Bloemfontein, RSA; J.F. Mustard, Hamilton, Canada; R.D. Neirinckx, Buckinghamshire, U.K.; A.M. Peters, London, U.IC; H. Pieters, Bloemfontein, RSA; C. Rosendorff Parktown, RSA; H. Sinzinger, Vienna, Austria; J. Vermylen, Leuven, Belgium; P. Wessels, Bloemfontein, RSA.

 

4th Meeting Cologne 1987:

 

Christoph Kessler, a neurologist who recebtly moved to Lubeck and just preparing his Dozent (associate professorship), was ambitiously organizing a conference aiming in particular to assess the role of platelet labeling in carotid artery disease.

List of Participants:

J. Bannenberg, Amsterdam, NL; W. Becker, Wurzburg, Germany; M. Brenner, Homburg/Saar, Germany; G.V. Desir, New Haven, USA; M.IC Dewanjee, Rochester, USA; A.J. Funke Kupper, Amsterdam, NL; D.A.J. Galvin, London, U.K; M. Goldman, Birmingham, U.K; M.R Hardeman, Amsterdam, NL; R.A. Harper, London, U.K.; W.D. Heiss, Koln, Germany; H. Henningsen, Heidelberg, Germany; M. Hipp, Koln, Germany; V. Hossmann, Koln, Germany; Ch. Kessler, Koln, Germany; T. KniEert, Berlin, Germany; J.P. Lavender, London, U.K; H. Louwes, Groningen, NL; J. Martin-Comin, Barcelona, Spain; A.C. Meek, London, U.K.; G. Modder, Koln, Germany; A. Moisan, Rennes, France; G. Pawlik, Koln, Germany; J.N. Petrovici, Koln, Germany; R Reuther, Heidelberg, Germany; E.B: Ringelstein, Aachen, Germany; M. Rotsch, Heidelberg, Germany; E. Schell-Frederick, Koln, Germany; H. Sinzinger, Vienna, Austria; J.R Stratton, Seattle, USA; M.L. Thakur, Philadelphia, USA; F.W.A. Verheugt, Amsterdam, NL; P. Voosen, Koln, Germany.

 

5th Meeting Vienna 1989:

The 5th International Symposium in September 1989 m Vienna was organized by Helmut Sininger with the helping hand of Susi Granegger, together with Mathew Thakur. There have been nearly hundred participants from over Europe, some came from the United States, and even from South-Africa and Japan. The new findings presented during the conference have been lively discussed. The atmosphere was really familiar, the participants had much fun during the trips, for instance to the Monastery Klosterneuburg and to the oldtimer car museum in Stockerau, which is owned by our colleague Gerry Brandstetter, the Head of the Department of Internal Medicine and Director of the county hospital in Stockerau.


Gerry Brandstetter in one fo this oldtimers at the museum in Stockerau

List of participants:

N. Arimizu, Chiba, Japan; Ch. Auinger, Vienna, Austria. P.N. Badenhorst, Bloemfontein, RSA; K Bakos, Praha, Czechoslovakia; W. Becker, Erlangen, Germany; R Beer, Marburg, Germany, P.C.L. Beverley, London, U.K; P. Blauenstein, Villigen, Switzerland; F. Bock, Vienna, Austria: M. Bock, Manchester, U.K; A. Bockisch, Bonn, Germany; H. Brenner, Vienna, Austria; M. Chianelli, Rome, Italy; P. Chiba, Vienna, Austria; B. Collet, Rennes, France; M. DeRoo, Leuven, Belgium; M.K Dewanjee, Miami, USA; D. Dodig, Zagreb, Yugoslavia; M.D. Ezekowitz, New Haven, USA; RA. Fawwaz, New York, USA; T. Feichtenschlager, Vienna, Austria; P. Fitscha, Vienna, Austria; J. Fortynova, Praha, Czechoslovakia; J. Hancevic, Zagreb, Yugoslavia; M.R. Hardeman, Amsterdam, NL; P.H. Hasler, ViUigen, Switzerland; A.duP. Heyns, Bloemfontein, RSA; D.B. Hocken, London, U.IC; R Hofer, Vienna, Austria; H. Hoffken, Marburg, Germany; K Itoh, Sapporo Japan; D. Ivancevic, Zagreb, Yugoslavia; H. Jackson, Manchester, U.IC; J. Johansen, Odense, Denmark; K Joseph, Marburg, Germany; C. Kessler, Liibeck, Germany; G. Kleinpeter, Vienna, Austria; Ch. Kolbl, Vienna, Austria; KF. Kotze, Bloemfoatein, RSA; A. Kroiss, Vienna, Austria; K Lange, Marburg, Germany; J. Lecloirec, Rennes, France; N. Colas Linhart, Paris, France; M. Livakovic, Zagreb, Yugoslavia; J.T. Locher, Aarau, Switzerland; F. Lomeaa, Barcelona, Spain; O. Loreal, Rennes, France; G. Lupattelli, Perugia, Italy; J. Marienhagen, Erlangen, Germany; J. Martin-Comin, Barcelona, Spam; F. Mata, Palma de MaUorca, Spain; J.G. McAfee, Washington, USA; C.N. McCollum, London, U.IC; A. Moisan, Rennes, France; L. Mortehnans, Leuven, Belgium; Ch. Muller, Vienna, Austria; I. Novak-Hofer, Villigen, Switzerland; P. Oehr, Bonn, Germany; Z.K Oster, Stony Brook, USA; G. Perneczky, Vienna, Austria; H. Pieters, Bloemfontein, RSA; B.S. Poulsen, Odense, Denmark; B. Pramsohler, Villach, Austria; F. Rauscha, Vienna, Austria; M. Roca, Barcelona, Spain; ICG. Schmidt, Odense, Denmark; K Scholz, Villach, Austria; P.A Schubiger, Villigen, Switzerland; A. Schwarz, Frankfurt, Germany; KL. Sharma, Maachester, V.K; A. Signore, Rome, Italy; K Siniinger, Vienna, Austria; E. Strobl-Jager, Vienna, Austria; J. Stuyck, Leuven, Belgium; M.L. Thakur, Philadelphia, USA; L. Toujas, Rennes, France; J.K Turner, Fremantle, Australia; K Uno, Chiba, Japan; I. Virgolini, Vienna, Austria; M. Vopatova, Praha, Czechoslovakia; G. Weidlich, Vieana, Austria; V. Weiler, Vienna, Austria; K Weiss, Vienna, Austria; P. Winter, Bonn, Germany.



6th Meeting Barcelona 1992:








The symposium in Barcelona, the best and largest one up to this time, organized by Jose Martin-Comin and his coworkers in November 1992, was attended by about 130 investigators from 20 different countries (among them 14 European countries). A total of 87 research papers were presented (General 6, Peptides 1, Platelets 22, Leucocytes 29, Erythrocytes 2, Monocloaal Antibodies 12, IgG 8, Others 7) and ample time was provided for after session and round table discussions. Overall, it was clearly evident that the merger of new technologies has presaged an exciting period in the field of diagnostic imaging with radiolabeled blood components. The whole meeting, including the social events, such as the trip to the Codorniu sparkling wine cellar m the mountains, and the wonderful mediterranean atmosphere and pleasant sunny climate of Barcelona, have been very well accepted by the participants. The dinner for the Board of Directors m the restaurant Set Portes at the port was an endless atherogenic journey through the Catalan cuisine.




Some of the colleagues from the Organizing Committee in Barcelona

List of participants

V. Alvarez, Princeton, USA; P.Angelberger, Vienna, Austria; P.Badenhorst, Bloemfontem, RSA; M.T. Bajen Lazaro, Barcelona, Spain; J. Banzo Marraco, Zaragoza, Spain; A. Baroli, Novara, Italy; P. Bass, Barcelona, Spain; A. Bastos-Lima, Porto, Potugal; W. Becker, Erlangen, Germany; P. Bernard, Marseille, France; M. Bernardo Filho, Rio de Janeiro, Brazil; M.H. de Bois, Leiden, NL; J. Buscombe, London, UK; J. Caix, Bordeaux, France; I. Carrio, Barcelona, Spain; F. Casals, Barcelona, Spain; M. Castell Fabrega, Barcelona, Spain; A. Catafau, Barcelona, Spain; M. Chianelli, London, UK; F. Corstens, Nijmegen, NL; M.I. Cotta Cardoso, Porto, Portugal; D.J. Coughin, Princeton, USA; I. Couret, Montpellier, France; C. de Labriolle-Vaylet, Paris, France; M. de Sequera Rahola, Sta. Cruz de Tenerife, Spain; R Dean, Londonderry, USA; M.K Dewanjee, Miami, USA; F.M. Domenech Tome, Barcelona, Spam; M.D. Ezekowitz, New Haven, USA; M.R Fernandez Espma, Barcelona, Spain; G. Firat, Izmir, Turkey; A.M. Forster, Bucks, UK; J: Fortunato, Porto, Portugal; M. Fraile Lopez-Amor, Barcelona, Spain; A. Furno, Bologna, Italy; A. Garcia, Barcelona, Spain; A. Garcia Burillo, Barcelona, Spam; J.R. Garcia Garzon, Barcelona, Spain; J.M.Gonzalez, Baroelona, Spain; D.A. Goodwin, Palo Alto, USA; J.L. Gordon, Oxford, UK; S. Granegger, Vienna, Austria; R. Herranz, Barcelona, Spain; M. Huguet Panella, Barcelona, Spam; V. Ivanceviv, Gottingen, Gemany; B. Jansson, Huddinge, Sweden; K Hazra,' Agra, India; R Kinne, Erlangen, Germany; KF. Kotze, Bloemfontein, RSA; A. Kroiss, Vienna, Austria; G. Landonio, Milano, Italy; D. Lasa, Madrid, Spain; J. Locher, Aarau, Switzerland; F. Lomena CabaUero, Barcelona, Spain; J. Looman, Petten, NL; K Louwes, Groningen, NL; L. Lusiani, Castel&anco, Italy; L. Mairal Padro, Barcelona, Spam; M.J. Marek, Albuquerque, USA; J. Martin-Comin, Barcelona, Spain; M.L. Martinez Pueyo, Madrid, Spain; F. Mata, Palma de Mallorca, Spain; M. Minoves Pont, Barcelona, Spain; A. Moisan, Rennes, France; J. Mora Salvado, Barcelona, Spain; M. Moragas, Barcelona, Spain; L. Mortelmans, Malvern, USA; M.A. Muxi, Barcelona, Spain; J. Pavia, Barcelona, Spain; A.M. Peters, London, UK; C. Piera, Barcelona, Spain; F. Pons Pons Barcelona, Spain; N. Prandmi, Ferrara, Italy; M.L Prat Elias, Barcelona, Spain; E. Prats Rivera, Zaragoza, Spain; L Ramirez, Barcelona, Spam; M. Ramos, Barcelona, Spain; M. Ramos Marquez, Barcelona, Spain; Y. Ricart, Barcelona, Spain; E. Riera, Barcelona, Spain; M. Roca, Barcelona, Spain; G.M. Sacchetti, Novara, Italy; M. Sala Suarez, Barcelona, Spain; C. Sampson, Cambridge, UK; T. Schail>le, Malvern, USA; G.R Schinella, La Plata, Argentma; KG. Schmidt, Odense, Denmark; M.I. Segarra Merino, Barcelona, Spain; J. Setoain, Barcelona, Spaia; F.J. Setoam Perego, Barcelona, Spam; K Seybold, Aarau, Switzerland; A. Signore, Rome, Italy; H. Sinzinger, Vienna, Austria; S. Solanski, Cambridge, UK; B. Soriano Borras, Barcelona, Spain; F. Spmelli, Milano, Italy; S.C. Srivastava, New York, USA; M.A. Sweetlove, Bloemfontein, RSA; M.L. Thakur, Philadelphia, USA; G. Torres, Barcelona, Spain; K Uno, Chiba, Japan; C. Van Neron, Leuven, Belgium; I. Virgolini, Vienna, Austria; I.M. Wedebye, Tommerup, Denmark; R Weiner, Farmington, USA;

 

7th Meeting New Haven 1995:

After some economic difliculties at the beginningof the organizing work for the 7th Symposium of the
ISORBE, Michael D. Ezekowitz has been very successful and the participants joined a very interesting meeting again. As a matter of fact, the number of American participants was quite high, on the other hand the one of Europeans rather low. It has been a pleasure to visit the old historical buildings at the Yale University campus and for some of the participants it has been the first time to get a look on a PET imaging center.





A street festival with lots of music and special food and last but not least the Volvo tennis tournament, where Mike was able to organize tickets for the participants of the symposium, were enjoyable social events. Plenty of sun and warm summer weather were accompanying the entire conference. For many of us it has been the first time to attend ATP-tennis at the center court, especially to see quarter- and semi-finals - with top-players as Boris Becker, Sergi Bruguera and Mats Wilander - of such an important tournament, which finally Andre Agassi won.

List of participants:

J. Arrighi, New Haven, USA; J. Banzo, Zaragoza, Spain; J. Barrett, N. Billerica, USA; M. Bernardo Filho, Rio de Janeiro, Brazi1; T. Biscotti, Chatsworth, USA; J. Buscombe, London, UK; L. Coetzee, Bloemfontein, RSA; P.D. Crane, N. Billerica, USA; A. Crocker, N. Billerica, USA; E. Daher, New Haven, USA; D. Damphousse, N. Billerica, USA; P.A. de Lima, Rio de Janeiro, Brazil; M.K Dewanjee, Miami, USA; H. Dey, New Haven, USA; K Eissler, Copiague, USA; M.R Fernandez Espma, Barcelona, Spain; M. D. Ezekowitz, New Haven, USA; A.M. Forster, Buckinghamshire, UK; R.S. Freitas, Rio de Janeiro, Brazil; A. Furno, Bologna, Italy; J. Glajeh, N. Billerica, USA; S. Granegger, Vienna, Austria; B. Gutfilen, Rio de Janeiro, Brazil; O. Hatano, Chiba, Japan; S. Hemingway, N. Billerica, USA; G. Karanikas, Vienna, Austria; J. Kuyama, Chiba, Japan; B.R. Lme, Albany, USA; J. Lister-James, Londonderry, USA; J.T. Locher, Aarau, Switzerland; H. Louwes, Groaingen, NL; J. Martin-Comin, Barcelona, Spam; J. McAfee, Rochester, USA; RC. Mease, Washington, USA; A. Moisan, Rennes, France; G.J. Momssey, London, Canada; B. Mosing, Vienna, Austria; B.R. Moyer, Londonderry, USA; K Ozker, Milwaukee, USA; H. Pieters, Bloemfontem, RSA; N. Prandini, Ferrara, Italy; T. Prangere, Lille, France; E. Prats, Zaragoza, Spain; T. Rees, Chatsworth, USA; M. Roca, Barcelona, Spain; E.IC Rocha, Rio de Janeiro, Braiil; M. Rodrigues, Vienna, Austria; C. Sampson, Cambridge, UK; A. Signore, Rome, Italy; H. Siniinger, Vienna, Austria; V.E. Soroa, Buenos Aires, Argentina; S.C. Srivastava, Upton, USA; M.L. Thakur, Philadelphia, USA; K Uno, Chiba, Japan; B.l. Zaret, New Haven, USA.


8th meeting Rome 1997:




The 8th ISORBE Congress, organised by Alberto Signore, was held on the 24th-27th May 1997 in Castel Gandolfo, Rome. This international congress was devoted to the presentation and discussion of the latest advances in nuclear medicine in the study of infection, inflammation, atherosclerosis and thrombosis. The symposium was attended by 138 participants hailing from 27 countries. The scientific programme of the congress included a total of 117 presentations: 14 invited lectures, 42 oral papers and 61 poster presentations. All of these being presented during the course of an opening symposium, two basic inflammation and radiopharmacy sessions, four clinical inflammation/infection sessions, two atherosclerosis and thrombosis sessions and four poster sessions.
The organising committee wisely took the view that nuclear medicine should be inter-related with other medical specialities, so there were a number of clinical medical societies involved in the organisation, and the different working sessions benefited from the participation of clinical, physiological, pathological and immunological experts.
The Congress began with a symposium on the pathogenesis, diagnosis and treatment of atherosclerosis, given by Professors R. Ross, V. Fuster, H. Sizinger and A. Corsini. During this symposium the most recent advances in the cellular and molecular bases of the condition, its pathogenesis and pharmacological control were discussed, as well as the role of nuclear medicine in this field. In the study of infection/inflammation special emphasis was given to research of new radiopharmaceuticals based on a better understanding of the pathophysiology of the inflammation, such as the studies carried out with cytokines and endothelial activation molecules.
In addition to the extensive scientific programme, those attending could also enjoy the wonderful countryside that surrounds the Villa Montecucco, especially Lake Albano, and make short visits to the Eternal City of Rome.
During the closing ceremony 4 prizes were awarded to the best presentations, with the winners being Doctors C. Van der Laken, E. Procaccini, S. Gratz and F. Jamar. In the choice of this pieces of research, devoted to cytokines labelling (interkeukin 1 and 2, endothelial activation molecules (anti-E selectin Fab) and new fragments of anti-granulocyte antibody, recognition was given to the search for future alternatives to conventional cell labelling techniques.

8th ISORBE Congress Participants: Alexander E., UK; Alonso-Farto J.C., Spain; Mrs. Alonso-Farto, Spain; Andreani D., Italy; Annovazzi A., Italy; Arca M., Italy; Archimandritis S.C., Greece; Arnold A., USA; Askienazy S., France; Askienazy M., France; Balink H., Holland; Barat J.L., France; Barone R., Rome; Barzin P.J., The Netherlands; Becker W., Germany; Behamdouni M., Canada; Bertrand-Barat J., France; Blower P.J., UK; Boccaletto F., Italy; Bowden A., UK; Buchmann M., Norway; Burroni L., Italy; Buscombe J.R., UK; Cangi, Italy; Castelli, Italy; Castorina L., Italy; Centi-Colella A., Italy; Cornaglia G., Italy; Chianelli M., Italy; Corsini A., Italy; Corstens F.H.M., The Netherlands; Crane P.D., USA; De Antoni M.G., Italy; D'Errico G., Italy; Ellis B., UK; Ezekowitz M., USA; Farrar G., UK; Fazio F., Italy; Fernandez Espina M.R., Spain; Forster A., UK; Furno A., Italy; Fuster V.; Galli G., Italy; Garganefe M.C.; Garron J.Y., France; Giacalone P.,Italy; Goldenberg D., USA; Granegger S., Austria; Grassi A.M., Italy; Gratz S., Germany; Gunasekera R., UK; GÜngor F., Turkey; Hauser W., Canada; Hoschl R., Australia; Hung J.C., USA; Iurilli A.P., Italy; Jamar F., Belgium; Jones J.M., UK; Kalauz M., Croatia; Karanikas G., Austria; Karonen S-L, Finland; Klem J.A., USA; Kotze H.F., South Africa; Lazzeri E., Italy; Leaver J.P., UK; Lee K.B., Korea; Leimer M., Austria; Liberatore M., Italy; Locher J., Switzerland; Maggi E., Italy, Martin-Comin J., Spain; Mather S.J., UK; Maurea S.,Italy; Maussier M.L., Italy; McAfee J., USA; Medina M., Italy; Mire-Sluis A., USA; Moisan A., France; Monton C., Spain; Moyer B.R., USA; Nardi G., Italy; Neumann I., Austria; Nielson J.T., Denmark; Ombresi D., Italy; Orlando P., Italy; Orlando V., Italy; Ormstead H.G., Norway; Overmyer T.A., UK; Oyen W.J.G, The Netherlands; Paganelli G., Italy; Pallone F., Italy; Parisella M.G., Italy; Pauwels E.K.J., The Netherlands; Pearce J.H., UK; Piffanelli A., Italy; Ponza F., Italy; Poropat M., Croatia; Poti C., Italy; Pozzilli P., Italy; Prandini N., Italy; Prangere T., France; Prats E., Spain; Procaccini E., Italy; Prosperi D., Italy; Rademacher T.W., UK; Roca M., Spain; Rodrigues M., Austria; Ronga G., Italy; Ross R.; Rouma G., Belgium; Sampson C., UK; Serra F., Italy; Squame F., Italy; Shapiro B., USA; Sharma H.L., UK; Sinzinger H., Austria; Sobal G., Austria; Soroa V.E., Argentina; Signore A., Italy; Spagnoli L., Italy; St Martin S., Canada; StrÖmberg S., Finland; Szasz, I., Canada; Thakur M.L., USA; Van Beers D., Belgium; Van der Laken C.J., The Netherlands; Van Haelst J.P., Belgium; van Wyk V., South Africa; Varraso Italy; Varoglu E., Turkey; Vaylet C., France; Ventroni G., Italy; Violi F., Italy; Wiseman G., USA; Zsinka L., Hungary.

 

9th ISORBE Congress

The 9th International Symposium on Radiolabeled Blood Elements has taken place from October 20th to October 23rd in the Campus of the Universidade do Estado do Rio de Janeiro, in Rio de Janeiro, Brazil. Rio de Janeiro is a beautiful city, with famous beaches, hills, typical food, special music and with a pleasant people that live there. This was the first time that a scientific event of the International Society on Radiolabeled Blood Elements happened in Latin American. More than one hundred papers were presented as invited lectures or oral papers or posters for colleagues from several countries. There were 117 participants from Brazil and other countries far away countries as Finland, Turkey and Australia. The 9th International Symposium on Radiolabeled Blood Elements has provided an excellent opportunity for the presentation and discussion of the latest achievements of nuclear medicine techniques and radiopharmaceuticals for the study of inflammation, infection, oncology and therapy using radiolabeled blood. The topics presented as invited lectures have permitted excellent discussions: (i) basic aspects of the inflammation process and the immunogenetics in the transplantation of organ, (ii) methods and the use of labeled antibodies, peptides and white blood cells in nuclear medicine, (iii) current US regulations and pharmacy practice standards applicable to blood element labeling in a commercial nuclear pharmacy, (iv) technetium-99m-labeled biotin and infecton, (v) nuclear medicine in the evaluation of ovarian and colon and rectal cancer and radiolabeled peptides for therapy, (vi) nuclear imaging in atherosclerosis, (vii) synthetic and bioengineered products in nuclear medicine and (viii) drug interaction in the labeling of red blood cells. There was a special lecture "Have faith in your radiopharmaceuticals - The Charles Sampson Memorial Lecture". The speaker was our colleague Malcolm Frier that with a strong emotion presented this lecture to remember Charles Sampson. Dr. Mathew Thakur was the responsible of the Scientific Committee to choose the four best papers presented in the 9th ISORBE, two oral and two poster to be awarded. These were:

  1. Synthesis, biodistribution and dosimetry studies of 123I-labelled annexin V in mice: a potential SPECT-ligand for visualisation of apoptotic cells. C. Lahorte, F. Dumont, G. Slegers, C. Van de Wiele, R.A. Dierckx from University of Gent, Belgium.
  2. Labelling of ceftizoxime with 99mTc. V. Gomes-Barreto, F. Iglesias, M. Roca, F. Tubau, J. Martin-Comin a collaboration between Spain and Brazil.
  3. Tc-99m HMPAO white blood cell scintigraphy in acute appendicitis patients with equivocal clinical presentation. F. Gungor, S. Ozugur, T. Colak, H. Bozan, A. Yildiz from Akdeniz University, Turkey.
  4. Labelling of the anti-elastin monoclonal antibody with technetium-99m using 2-iminothiolane. M.B.N. Oliveira, C.R. Silva, A.C. Braga, A. Caldeira-de-Araujo, M. Bernardo-Filho from University of Rio de Janeiro, Brazil.

Symposium Participants: Prangere Thierry, Sirkka-Liisa Karonen, Kairemo Kalevi, Veiga Jorge, Lasa Perez Dionisio, Granegger Susanne, Tomas Maria, Cavalcante Carlos, Locher Johannes, Palestro Christopher, Sobal Grazyna, Ramos Farias Moreno Silvana, Linkowski Faintuch Bluma, Dantas Flavio, Zabala Prisila, Capriles V.S., Prandini Napoleone, Moisan Annick, Ozker Kutlan, Firat Gungor Ahmet, Baptista Santos Marco Aurelio, de Oliveira Chavez Erika Cristina, Hiller Bondarczuck Marli, Lahorte Christophe, Sciavom Duarte Paulo, Moraes Rogerio, Barat Bertrand, Frier Malcolm, Ertay Turkan, Diniz Simone, Leite Bruno, Franca de Mendonca Elitom, de Oliveira Aguiar Ronaldo, Dere Feliciano Glaucio, Burroni Luca, Gunasekera R., de Labriolle-Vaylet Claire, Ripoll Hamer Erica, Alonso-Farto Juan Carlos, Carneiro Michel, Nigri Flavio, Ferreira da Costa Rosario, Souza O. Jose Eduardo, de Souza Maciel Oduwaldo, Forstrom Lee, Serafim R. Bernardo, Camargo Bernardo Luciana, Varraso Antonio, Prats Enrique, Cardoso de Souza Conceicao Rejane, Braga A.C.S., Avila A.S., Caldeira de Araujo Adriano, Signore Alberto, Buchpiguel Carlos Alberto, Ribeiro da Silva Claudia, Pagano G. da Silva Constancia, Pearson Daniel, Tabak Daniel, Machado do Mattos Deise Mara, Regio Moraes Edison, Boasquevisque Edson, Kotlyarov Eduard, Garcia Eloy J., Verdera Presto Emilia Silvia, Braga Francisco, Sinzinger Helmut, Oliveira Joelma F., Buscombe John R., Martin-Comin Jose, Oliva Gonzales Juan P., Britton Keith E., Seifert Katherine L., Oliveira Marcia B.N., Younes Ibrahim M., Roca Engronat Manuel, Rodrigues Margarida, Exposito Penas Maria, Gomes Maria Luiza, Bernardo Filho Mario, Thakur Mathew L., Stabin Michael, Boerman Otto C., Gonzales Espinoza Patricio Orlando Jose, Baum Richard, Levy Cavalcanti Jales Roberto, de Souza Freitas Rosemeire, Das Satya S., Cardoso Albert N., Soroa Victoria Ester, Oyen Wim J.G., Rodrigues Motta Anna Paula, Aleixo Luis Claudio, Bastos Miguel Angelo, Braghiroli Ana Maria, Laufer Gustavo, Pecanha Muzy Dias Aline, Moreira Monamaldo Costa Thadeu Estevam, Figueiredo Soares Scheila, Figueiredo de Melo Suzana, Masioli Marco Antonio, dos Santos Lins Gean Bernardo Xavier, Salehi Nouria, Theodoro Boullosa Lidia, Roberto Avila C. Bezerra Jose, Ribeiro Madke Rafael, Almeida Maria Janilde, Ferreira da Costa Rogerio, Shaskolsky I., Lazzeri Elena, Nilson Elisa, Vivante Hugo A., Fonseca Souza Joseane, Paiva Proenca Martins Flavia, Nicolini Jorge Oswaldo, Manhaes de Souza Ricardo A., Miranda Jose R. A..

 

 

 


TIME-TABLE OF CONFERENCES 

 

1st International Symposium on Radiolabeled Blood Cells.
September 1979, Yale

University School of Medicine, New York, USA.
Organization: M.L. Thakur, A. Gottschalk

Proceedings: In-111 labeled neutrophils, platelets and lymphocytes.
Eds.: M.L. Thakur, A. Gottschalk, Trivirum Pub. Co., New York, 1980.

2nd Radiolabeled Cellular Blood Elements.
August 29 - September 9, 1982, Maratea,
Italy, NATO ASI.

Organization: M.L. Thakur, M.D. Ezekowitz, M.R. Hardeman
Proceedings: Radiolabeled cellular blood elements. Eds.: M.L. Thakur, M.R Hardeman, M.D. Ezekowitz. Plenum Pub. Co., New York, 1985


3rd Conference on Radionuclide Labeled Cellular Blood Elements: Application in Atherosclerosis and Thrombosis.
February 3 - 6, 1986, University of the Orange Free State, Bloemfontein, South Africa.

Organization: A. du P. Heyns, P.N. Badenhorst, M.G. Lotter
Proceedings:
Conference on radionuclide labeled cellular blood elements: Applications m Atherosclerosis and Thrombosis. Ed.: A. du P. Heyns. Publ. South African Medical Research Council, Parow, 1986.



4th International Symposium on Radiolabeled Platelets.
May 28 - 29, 1987. Hotel
Mondial, Cologne. Germany

Organization: J.N. Petrovici, Ch. Kessler, G. Modder
Proceedings:
Clinical Applications of Radiolabeled Platelets. Eds.: Ch. Kessler, M.R
Hardeman, K Hennmgsen, J.N. Petrovici. Kluwer Academic Publ., Dordrecht, NL, 1990.

 

5th International Symposium on Radiolabeling of Cellular Blood Elements.
September 10 - 14, 1989, Vienna, Austria Foundation of the
INTERNATIONAL SOCIETY OF RADIOLABELED BLOOD ELEMENTS ( ISORBE ).

First President: Mathew L. Thakur
Organizing Chairmen: H. Sinzinger and M.L. Thakur
Local Organization: P. Fitscha, Ch. Miiller, Eva Strobl-Jager, Irene Virgolini, V. Weiler 
Abstracts: Nuclear Medicine Research Vol 3. RadiolabeRed Cellular Blood Elements. Eds.: KF. Sinzinger, M.L. Thakur.
Proceedings:
Progress in clinical and biological research. Vol. 355. Radiolabeled Cellular Blood Elements. Eds.: H. Sinzinger, M.L. Thakur. Publ Wiley-Liss Inc. New York, 1990.

 

6th International Symposium on Radiolabeled Blood Elements.
NATO Advanced Research Workshop. November 23 - 27, 1992, Barcelona, Spain

Second President: Helmut Sinzinger
Advisory Council: M.L. Thakur, J.G. McAfee, H. Sinzinger, J. Martin-Comin
Local Organization: J. Martin-Comin, M. Roca, C. Piera, F. Lomena
Proceedings:
Radiolabeled Blood Elements. Recent advances in techniques and applications.
Eds.: J. Martin-Comin, M.L. Thakur, C. Piera, M. Roca, F. Lomena. NATO ASI series vol.
262, Plenum Press, New York, 1994.

 

Pre-congress Meeting during the European Association of Nuclear Medicine Congress
August 20, 1994, Dusseldorf; Germany

Organization: H. Sinzinger

 

7th International Symposium on Radiolabeled Blood Elements.
August 16 - 19, 1995, Yale University, New Haven, USA

Third President: Jose Martin-Comin
Honorary President: John G. McAfee
Course Director: M.D. Ezekowitz
Local Organization: M.D. Ezekowitz, J. Arrighi, Holley Dey, R Soufer, B.L. Zaret
Proceedings: Have not been published

 

Pre-congress Meeting during the European Association of Nuclear Medicine Congress
September 14, 1996, Copenhagen, Denmark

Organization: A. Signore, M. Chianelli

 

8th International Symposium on Radiolabeled Blood Elements.
May 24 - 27, 1997, Rome, Italy

Organizing President: A. Signore
Local Organization: M. Arca (Secretary), M. Chianelli, M. Liberatore, Maria L. Maussier, G. Paganelli, A. Piffanelli, P. Pozzilli, G. Ronga
Honorary Committee: D. Andreani, P. Biglioli, P. Bianchi, G. Camuzzini, A. Centi Colella, G. Faglia, F. Fazio, G. Galli, M. Gandolfi, G. Ricci
Scientific Committee: S. Askienazy, W. Becker, F. Corstens, M. Ezekowitz, J. Martin-Comin, S.J. Mather, A. Piffanelli, K Sinzinger, S. Srivastava, M.L. Thakur, F. Violi
Abstracts: Nuclear Medicine Communications
Proceedings
: Not decided at time of printing



9th International Symposium on Radiolabeled Blood Elements.
October 20-23, 1999 Universidade do Estado do Rio de Janeiro, Campus Rua São Francisco Xavier, 524 Rio de Janeiro, RJ, Brazil

Organizing President: M. Bernardo-Filho
Coordinator: E. Mendes Boasquevisque
Organizing Committee: M. Chianelli, P. Gonzales, M. Frier, M. Rodrigues, V.E. Soroa, S. Verdera, S. Srivastava
Local Committee: A.M. Braghirolli, A.C. de Araújo, C. Buchpiguel, C.R. Silva, C. Pagano, J.E. Pereira, J.F. Oliveira, M.B. Oliveira, M. Exposito Penas, M. Albernaz, M. Rebelo, R.J. Bezerra
Scientific Committee (International): W. Becker, J. Buscombe, J. Martin-Comin, A. Signore, H. Sinzinger, M. Thakur
Scientific Committee (Local): V.C. Nascimento, F. Braga, R.L. Jales, E.A. Araújo, M. Bernardo-Filho, E.M. Boasquevisque, M.A. Martins, C.A. Lacerda
Abstracts: Published in Nuclear Medicine Communication
Proceedings:

 

BOARD OF ISORBE


1989 - 1992

President:
Mathew L. Thakur (Philadelphia, USA)

Secretary:
John G.McAfee(Washington, USA)
 
Treasurer:
Helmut Sinzinger (Vienna, Austria)

Executive Committee:
W. Becker (Erlangen, Germany), M.K Dewanjee (Miami, USA), M.E. Ezekowitz (New Haven, USA), D.A. Goodwin (Palo Alto, USA), M. Hardeman ( Amsterdam, The Netherlands), A. duP. Heyns (Bloemfontein, South Africa), C. Kessler (Koln, Germany), P. Lavender (London, U.K.), J. Martin-Comin (Barcelona, Spain), A.M. Peters (London, U.K.), K Uno (Chiba, Japan)




1992 -1995

President:
Hehnut Sinzinger (Vienna, Austria)

Immediate Past President:
Mathew L. Thakur (Philadelphia, USA)

Secretary:
Michael D. Ezekowitz (New Haven, USA)

Treasurer:
Jose Martin-Comin (Barcelona, Spain)

Board of Directors:
P.N. Badenhorst (Bloemfontein, South Africa), R Baum (Frankfurt, Germany), W. Becker (Gottingen, Germany), F. Corstens (Nijmegen, The Netherlands), M. K Dewanjee (Miami, USA), A. Driedger (London, Canada), M.C. Gil (Santiago, Chile), D.A. Goodwin (Palo Alto, USA), M. Hardeman (Amsterdam, The Netherlands), K Hazra (Agra, India), A. du P. Heyns (Bloemfontein, South Africa), RM. Lambrecht (Sidney, Australia), J.P. Lavender (London, U.K), J.T. Locher (Aarau, Switzerland), F. Lomena (Barcelona, Spain), J.G. McAfee (Bethesda, USA), A. Moisan (Rennes, France), A.M. Peters (London, U.K.), A. Signore (Rome, Italy), K Uno (Chiba, Japan)




1995-1997

President:
Jose Martin-Comin (Barcelona, Spain)

Honorary President:
John McAfee (Bethesda, USA) Immediate Past

President:
Helmut Sinzinger (Vienna, Austria)

Secretary:
Alberto Signore (Rome, Italy)

Treasurer:
Wolfgang Becker (Gottingen, Germany)

Board of Directors:
P.N. Badenhorst (Bloemfontem, South Africa), M. Bernardo-Filho (Rio de Janeiro, Brazil), F. Corstens (Nijmegen, The Netherlands), M. K Dewanjee (Miami, USA), M.D. Ezekowitz (New Haven, USA), Maria Cecilia Gil (Santiago, Chile), D.A. Goodwin Palo Alto, USA), K Hazra (Agra, India), RM. Lambrecht (Sidney, Australia), J.T. Locher (Aarau, Switzerland), Annick Moisan (Rennes, France), A.M. Peters (London, U.K), E. Prats Rivera (Zaragoza, Spain), Margarida Rodrigues (Vienna, Austria), C.B. Sampson (Cambridge, U.K.), Victoria E. Soroa (Buenos Aires, Argentina), S.C. Srivastava (Upton, USA), K Uno (Chiba, Japan)



1997-1999

President:
Wolfgang Becker (Gottingen, GE)

Honorary President:
John McAfee (Bethesda, USA)

Immediate Past President:
Jose Martin-Comin (Barcelona, Spain)

Secretary:
John Buscombe (London, UK)

Treasurer:
Margarida Rodrigues (Vienna,Austria)

Board of Directors:
P.N. Badenhorst (Bloemfontein, South Africa), M.D. Ezekowitz (New Haven, USA), M.C. Gil (Santiago, Chile), C.B. Sampson (Cambridge, UK), K. Uno (Chiba, Japan), S.C. Srivastava (Upton, USA), K. Azra (Agra, India), M.Chianelli (Rome, Italy), F. Corstens (Nijmegen, NL), R.M. Lambrecht (Sidney, Australia), V.E. Soroa (Buenos Aires, Argentina), M.K. Dewanjee (Miami, USA), A. Moisan (Rennes, France), D.A. Goodwin (Palo Alto, USA), M.A. Peters (London, UK), M. Bernardo-Filho (Rio de Janeiro, Brazil), J.T. Locher (Aarau, Switzerland), E. Prats Rivera (Zaragoza, Spain).

 

1999-2001

President:
Alberto Signore (Rome, Italy)

Honorary President:
John McAfee (Bethesda, USA)

Immediate Past President:
Wolfgang Becker (Gottingen, GE)

Secretary:
Enrique Prats Rivera (Zaragoza, Spain)

Treasurer:
Margarida Rodrigues (Vienna, Austria)

Board of Directors:
P.N. Badenhorst (Bloemfontein, South Africa), M. Bernardo-Filho (Rio de Janeiro, Brazil), J. Buscombe (London, UK), F. Corstens (Nijmegen, NL), M.K. Dewanjee (Miami, USA), M.D. Ezekowitz (New Haven, USA), M.C. Gil (Santiago, Chile), D.A. Goodwin (Palo Alto, USA), K. Azra (Agra, India), R.M. Lambrecht (Sidney, Australia), J.T. Locher (Aarau, Switzerland), A. Moisan (Rennes, France), W. Oyen (Nijmegen, The Netherlands), M.A. Peters (London, UK), V.E. Soroa (Buenos Aires, Argentina), S.C. Srivastava (Upton, USA), K. Uno (Chiba, Japan).

 


PRESIDENTS

 

1989 - 1992: Mathew L. Thakur
1992 - 1995: Helmut F. Sinzinger
1995 -1997: José Martin-Comin
1997 - 1999: Wolfang Becker
1999 - 2001: Alberto Signore
2001 - 2004: Margarida Rodrigues

 



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